Essay

Syphilis Origins Debate: When Did It Reach Europe?

A historical epidemiology guide to the syphilis origins debate, Treponema evidence, ancient DNA, and the Columbian versus pre-Columbian question.

Indexed essay December 3, 2025 By Devin Teichrow scienceHistorysyphilismedicineepidemiology

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syphilis origins debate

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By Devin Teichrow. Published December 3, 2025.

Overview

A historical epidemiology guide to the syphilis origins debate, Treponema evidence, ancient DNA, and the Columbian versus pre-Columbian question.

For a family of pathogens that has likely been with humanity since the dawn of agriculture, Treponema has a funny way of keeping its secrets.

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