Essay

Psilocybin vs Antidepressants: Meta-Analysis

A meta-analysis comparison of psilocybin and antidepressants for depression, with attention to study design, endpoints, and overstated certainty.

Indexed essay July 10, 2025 By Devin Teichrow depressionscienceclinical trialspsychiatrypsychedelics

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psilocybin antidepressants meta-analysis

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By Devin Teichrow. Published July 10, 2025.

Overview

A meta-analysis comparison of psilocybin and antidepressants for depression, with attention to study design, endpoints, and overstated certainty.

In the middle ages people feared ergot like a curse.

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