Lead source: PubMed Historical Pathogen Case Studies
What happened
Memories of Memórias: shaping a century of plague research and public health policy in BrazilFIRST REVIEW ROUND
Why it matters
This file matters because official outbreak tracking remains active even if publisher coverage is thin.
What changed in this run
Latest summary: The lead item has changed to Memories of Memórias: shaping a century of plague research and public health policy in BrazilFIRST REVIEW ROUND from PubMed Historical Pathogen Case Studies.
The lead item has changed to Memories of Memórias: shaping a century of plague research and public health policy in BrazilFIRST REVIEW ROUND from PubMed Historical Pathogen Case Studies.
Story volume increased from 3 to 4 clustered item(s) in the current window.
1 newly observed linked item(s) were added since the last saved snapshot.
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Over the past 125 years, the country has experienced cyclical outbreaks concentrated in the northeast, where ecological conditions support enzootic transmission among wild rodents and their fleas. While improved surveillance and control have reduced human cases in recent decades, the pathogen's zoonotic nature and potential for rapid spread in a changing climate underscore its enduring public health relevance. Often erroneously considered a medieval relic, the disease persists in natural foci, including Brazil, where it was introduced in 1899 via maritime trade.
They once guided clinicians in recognizing tabes dorsalis before Treponema pallidum was identified, and they remain useful when access to laboratory testing is limited or when patients present late with established deficits. This article examines the neurologic signs historically linked to tabes dorsalis and assesses their relevance in today's neurosyphilis diagnostics. These signs point to a characteristic pattern of sensory impairment-patchy loss of pain perception with absent deep-tendon reflexes-reflecting involvement of the dorsal roots, posterior columns, and peripheral sensory fibers.
The transcribed line list comprises of 3,255 incident cases and includes the following variables: national case serial number, age, sex, date of rash onset, date detected, village/locality, district, region, regional outbreak number, and national outbreak number. Over more than three thousand years, smallpox caused millions of deaths worldwide. Handwritten smallpox outbreak data from Somalia (1976-1977) were obtained from the World Health Organization by a Public Health England study team (now UK Health Security Agency).
Search for relevant literatures on plague that were published in the Web of Science Core Collection and PubMed database from January 1, 2016 to November 12, 2025.Bibliometric methods were adopted, and software including COOC 20.6, VOSviewer 1.6.20, and Anaconda were used to analyze the publication trend, distribution of institutions, national cooperation network, keyword co-occurrence clustering, and the annual variation trends. From 2021 to 2025, "Phylogenetic Analysis," "Public Health," and "Madagascar" newly entered the top 20 keyword list; the frequencies of "Black Death" and "Infectious Disease" increased significantly, while the frequencies of "Plague Vaccine" and "Prairie Dogs" remained relatively stable. The annual number of publications showed an overall fluctuating upward trend, with a significant growth rate from 2020 to 2021 (annual growth rate of 10.44%).
Publisher Coverage
No publisher coverage items are attached to this story yet.
Related Disease Intelligence
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Timeline
2026-05-15T05:46:162 item(s)2 source(s)
Baseline snapshot created with 2 clustered item(s) across 2 source(s).
PubMed Historical Pathogen Case Studies now includes deaths or fatal cases in the story frame.
PubMed Historical Epidemiology now foregrounds vaccination or vaccine policy in the story.
2026-05-18T18:15:373 item(s)3 source(s)
New publisher/source coverage joined this story cluster: The Conversation.
Story volume increased from 2 to 3 clustered item(s) in the current window.
1 newly observed linked item(s) were added since the last saved snapshot.
2026-05-18T21:51:104 item(s)3 source(s)
The lead item has changed to Eponymous neurologic signs of tabes dorsalis: A historical review (1846-1905). from PubMed Historical Pathogen Case Studies.
Story volume increased from 3 to 4 clustered item(s) in the current window.
1 newly observed linked item(s) were added since the last saved snapshot.
2026-05-19T22:03:434 item(s)2 source(s)
The lead item has changed to Memories of Memórias: shaping a century of plague research and public health policy in BrazilFIRST REVIEW ROUND from PubMed Historical Pathogen Case Studies.
Story volume increased from 3 to 4 clustered item(s) in the current window.
1 newly observed linked item(s) were added since the last saved snapshot.