Essay
Ebola in DRC and Uganda: Outbreak Update
Live outbreak notes on Ebola virus disease in DRC and Uganda, with what is confirmed, what remains uncertain, and why regional spread matters.
The Edge of Epidemiology
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Writing archive
Essays on outbreaks, evidence, disease history, ecology, neuroepidemiology, and the public arguments that gather around health.
Archive
Each entry keeps the essay connected to topic hubs, disease maps, and related work across the site.
Essay
Live outbreak notes on Ebola virus disease in DRC and Uganda, with what is confirmed, what remains uncertain, and why regional spread matters.
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How Korean War trench warfare, rodent ecology, and Hantaan virus turned a mysterious military outbreak into hantavirus history.
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A source-first guide to the MV Hondius hantavirus outbreak, Andes virus, cruise-ship exposure, travel risk, and what investigators could know.
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A source-aware look at a newly reported sexually transmitted fungal infection, including MSM networks, case evidence, transmission questions, and reporting limits.
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How ancient DNA, infectious disease pressure, immunity, and changing environments help explain genomic selection in West Eurasian populations.
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A framework essay for thinking about disease across deep time, infrastructure, migration, ecology, empire, and the systems civilizations build.
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The 1793 Philadelphia yellow fever epidemic as an early American public-health crisis shaped by urban ecology, politics, race, and mosquito-borne disease.
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A careful look at Viking movement, North Sea disease ecology, plague evidence, Norse voyages, and the limits of reconstructing medieval pathogen spread.
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A Pathogen Dispatch essay on tuberculosis, public-health capacity, drug resistance, airborne transmission, and why old diseases keep returning.
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Disease mortality in the American Revolutionary War, including battle deaths, smallpox, camp disease, military medicine, and eighteenth-century survival.
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Disease on the Oregon Trail, from cholera and dysentery to overland migration, sanitation, graves, and nineteenth-century westward travel.
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How yellow fever, mosquitoes, Saint-Domingue, military failure, and disease ecology helped destroy Napoleon’s North American empire plans.
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How smallpox threatened the American Revolution, why inoculation mattered, and how disease shaped military survival during the founding war.
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Smallpox, measles, malaria, diphtheria, enteric disease, and vector-borne fevers in early British North America before the Revolution.
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Why Old World pathogens devastated Indigenous Americans while New World diseases rarely reversed the catastrophe in Europe, Africa, and Asia.
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Ancient DNA, Yamnaya and steppe migrations, plague evidence, and how pathogen history intersects with population-genetic change.
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A careful look at disease, colonial disruption, Indigenous population collapse, Old World pathogens, and the limits of simple post-1492 stories.
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Shipboard disease ecology before modern medicine: scurvy, infection, crowding, ports, naval history, and the epidemiology of life at sea.
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Cocoliztli and Mexico’s sixteenth-century mystery epidemics, including retrospective diagnosis, colonial records, ancient DNA, and pathogen uncertainty.
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What ancient infections, inherited pathogens, and human prehistory can reveal about disease pressure before written medical history.
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Part two of a pre-contact Americas disease ecology series, focused on South America, isolation, endemic infections, and ecological context.
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Disease ecology in North and Central America before 1492, including isolation from Eurasian disease pools and Indigenous health context.
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A historical epidemiology guide to the syphilis origins debate, Treponema evidence, ancient DNA, and the Columbian versus pre-Columbian question.
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Ancient hookworm in the Americas, parasite geography, archaeology, migration, and why a tropical helminth complicates disease-history origin stories.
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What fossilized feces, archaeology, parasite evidence, diet, and microbial remains can tell us about ancient health and disease.
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A deep-time disease essay on the oldest known evidence for infection, cancer, parasites, and what paleopathology can reveal.
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A critical look at claims about history’s deadliest microbes, mortality estimates, infectious disease rankings, and what counts as a deadly companion.
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Leprosy, colonial rule, island isolation, stigma, and the public-health geography of empire in the South Pacific.
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The 1858 Staten Island quarantine hospital fire, immigrant disease fear, port quarantine, yellow fever panic, and public-health violence.
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What GLP-1 agonists might mean for migraine, headache biology, metabolic drugs, clinical evidence, and what remains speculative.
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A methods-first look at the U.S. life expectancy gap, why it sounds worse than it is, and what the counterfactuals imply.
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What a new LSD trial does and does not show about psychedelics for anxiety, trial design, clinical endpoints, and evidence limits.
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How cadaver shortages, grave robbing, riots, and medical education shaped the history of American anatomy and public trust.
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Why heat exposure may not age everyone equally, including climate risk, social vulnerability, occupational exposure, and epidemiologic measurement.
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Founder effects, population bottlenecks, rare disease risk, genetic ancestry, and why screening programs often follow history.
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How warmer weather, urbanization, vector range, travel, and ecological change are shifting infectious disease risks in 2025.
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A guide to the evidence on lithium and Alzheimer’s risk, including observational data, mechanisms, trial limits, and causal uncertainty.
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How paper mills poison science, why fake studies spread, and what scientific publishing loses when quantity beats credibility.
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A response to Eric Topol’s super-agers argument and the medical system needed for aging, prevention, function, and long-term health.
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Migraine brain fog, cognition, medication trade-offs, attack phases, and how cognitive symptoms complicate the lived burden of migraine.
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Why the word memetics faded while viral ideas, imitation, information spread, and cultural transmission kept shaping public life.
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A meta-analysis comparison of psilocybin and antidepressants for depression, with attention to study design, endpoints, and overstated certainty.
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The unsolved 1951 Pont-Saint-Esprit outbreak, ergot theories, poisoning claims, CIA rumors, and why retrospective diagnosis stays hard.
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Migraine is disabling and unevenly treated. Here is what the data says about who gets it, who lacks help, and why uncertainty remains.
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A short migraine research note from the American Headache Society meeting, focused on clinical questions, evidence gaps, and field direction.
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A risk-communication essay on melanotan nasal sprays, tanning peptides, sexual side effects, black-market marketing, and safety concerns.
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What fitness trackers and Apple Watch data are good for, where wearable measurements fail, and how to interpret consumer health metrics.
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A War Epidemiology chapter draft on the Justinianic Plague, military stress, empire, logistics, and disease pressure in 541 CE.
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A skeptical look at magnesium for sleep, mocktail marketing, supplement evidence, and why plausible mechanisms are not enough.
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A critique of dopamine detox claims, poorly trained brains, social media habits, reward systems, and pop-neuroscience oversimplification.
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Why melatonin is misunderstood, who may benefit, how timing matters, and where sleep supplement claims outrun the evidence.
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A public-health look at raw milk, foodborne pathogens, pasteurization, outbreak risk, and the evidence behind natural-food claims.
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A critique of “back to nature” wellness claims, synthetic panic, food fear, and why nature is not automatically safer.
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An evidence check on Rhonda Patrick’s vitamin D and dementia claims, observational studies, confounding, and supplement certainty.
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Why detox cleanses, supplement stacks, and smoothie cures misunderstand liver, kidney, and gastrointestinal physiology.
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How skin pigmentation, latitude, migration, colonial settlement, UV exposure, and sunburn risk collide when ancestry and place diverge.
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Why creatine may be underrated for people who could benefit, including muscle, aging, cognition claims, and supplement evidence limits.
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A statement of purpose for The Edge of Epidemiology: better science communication, disease history, public health, and evidence-aware writing.
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A public-health essay on early puberty, calories, growth, endocrine signals, obesity, and environmental explanations.
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Why strong opinions require due diligence, epistemic humility, evidence review, and a higher bar than vibes or tribal certainty.
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A reflection on scout mindset, certainty, tribalism, belief formation, and why changing your mind is part of serious reasoning.
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A risk-communication guide to artificial sweeteners, health headlines, cancer fears, confounding, and scapegoat nutrition claims.
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How gluten became a wellness panic, what celiac disease and sensitivity evidence actually show, and where food fear outruns data.
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What new stem cell trials mean for Parkinson’s disease, safety, endpoints, clinical promise, and why the field still has no cure.
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A methods essay on learning causal inference, epidemiology training, counterfactual thinking, and why the framework can feel brain-breaking.
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How diagnostic reclassification helped create the appearance of an autism epidemic, and what changing case definitions do to trend data.
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Why apparently monogamous birds often mate outside pairs, and what animal behavior teaches about ecology, genetics, and expectation.
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How health headlines can be technically true but misleading when baseline risk, relative risk, and absolute risk are left out.
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Why epidemiology did not have a replication crisis in the usual sense, but still ended up with a public trust crisis after COVID.
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Why obesity is not simply a dopamine deficiency, what reward biology suggests, and how simple neurochemical stories mislead.
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Why personality heritability is probabilistic, not destiny, and how genetics, environment, and uncertainty shape psychological traits.
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Why weak nutrition studies can make almost any food look carcinogenic, and how confounding, measurement, and multiple testing mislead.
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Why the relationship between cannabis and psychosis is not straightforward, including causality, confounding, dose, and psychiatric risk.
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A Devilish Diseases essay on chronic wasting disease, prions, wildlife ecology, deer populations, surveillance, and spillover anxiety.
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How endemic tropical diseases can affect childhood cognition, development, school performance, and long-term public-health inequality.
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How measles immune amnesia raises the stakes of vaccination, resurgence, outbreak control, and the hidden burden after infection.
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A practical overview of AI in healthcare, current applications, clinical promise, implementation limits, and risks of overclaiming.
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A personal and global-health look at epilepsy, seizure stigma, treatment gaps, public misunderstanding, and the burden of neurological disease.
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Examining why multiple sclerosis risk increases with distance from the equator, including latitude, vitamin D, genetics, and environment.
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A migraine research overview connecting neuroepidemiology, neuroscience, burden, treatment gaps, and recent literature.
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An introduction to neuroepidemiology, including neurological disease patterns, risk factors, populations, surveillance, and public-health methods.
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What is known about bivalve transmissible neoplasia, marine disease ecology, cancer transmission, and ecosystem risk.
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How bacteriophages could be used in food safety, water treatment, agriculture, environmental health, and sustainability.
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A guide to bacteriophages as a possible tool against antibiotic resistance, including medical uses, promise, and limits.
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A guide to oral GLP-1 agonists, obesity and type 2 diabetes treatment, clinical promise, delivery advantages, and evidence still needed.
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How koala retrovirus, habitat loss, climate stress, and infectious disease combine into a conservation and evolutionary health problem.
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The ancient canine transmissible venereal tumor, how a cancer crossed continents, and what transmissible cancers reveal about disease ecology.
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A holiday food-safety guide to foodborne illness, kitchen risk, turkey handling, pathogens, and how not to ruin Thanksgiving.
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A Devilish Diseases essay on Tasmanian devil facial tumor disease, transmissible cancer, wildlife ecology, and conservation risk.